Industry Outlook
Cardiac markers are the substances that are released into the blood stream during heart damage. These markers are detected with specialized immunoassays and are used for diagnosis, evaluation and monitoring of patients with suspected acute coronary syndrome. These markers are very useful when patients do not present ischemic chest pain and have non-diagnostic ECG. The common cardiac markers used for evaluation of acute coronary syndrome are troponin I & T, CK-MB and myoglobins. Other biomarkers studied in this report are less specific in nature, but are also used for further evaluation, in terms of damage to the system. Considering their usefulness, cardiac biomarkers are vital for diagnosis of acute coronary syndrome, acute myocardial infraction, and heart failure and renal diseases; prognosis and risk stratification of patients with coronary syndrome, and for patients that are undergoing pre- and post-reperfusion and interventions.
Globally increasing prevalence of cardiovascular diseases, rapidly changing lifestyle and dietary patterns, increasing pool of high-risk geriatric population, and persistent growth in the nature of point-of-care diagnostic solutions are the key factors driving the growth of the global cardiac markers market. Conversely, high cost and less specificity of certain tests may hold back the growth of this market. Intensive R&D initiatives and success of the use of cardiac biomarkers in detection of congenital coronary diseases are some of the aspects that will open future opportunities in this market.
"Troponin Tests to Remain the Largest Revenue Segment"
Troponin T and I enzymes are normal proteins that are vital for contractile apparatus of cardiac myocyte. These enzymes are released in the blood circulation between three and four hours of myocardial infraction and are detectable after up to ten days. Such long life of troponin allows for late diagnosis of myocardial infraction but are not successful in diagnosis of re-infraction. Higher uptake of troponin T & I tests is because these are more sensitive than creatine kinase (CK) and myoglobin. Monoclonal antibody tests are also being developed for detection of specific troponin T and cardiac specific troponin I. cardiac troponin are also used for diagnosis of chest pain in patients with non-diagnostic ECG. These tests are also used for prognosis of a myocardial infraction and identification of patients with high risk of cardiac events.
"Reagents and Kits, and Point-of-Care Testing to Remain the Market Leaders"
Based on products, the global cardiac markers market is classified into reagents and kits, and instruments (chemiluminescence, immunofluorescence, immunochromatography and ELISA). Between the two, the demand for reagents and kits is set to remain the highest during the forecast period. Low costs and greater purchase volume are the key factors considered for the dominance of this segment. However, with technological evolution, the demand for analyzer instruments will remain stable throughout the forecast period. The market growth of the instruments segment is set to remain the highest in emerging markets of Asia Pacific, Latin America and Middle East and Africa, where the rapid development of healthcare infrastructure is being witnessed. At present point-of-care (POC) immunoassays for several cardiac markers for troponin I & T, myoglobin and CK-MB are available in the market that deliver good quantitative and qualitative results comparable to traditional laboratory-based assays. POC cardiac markers are vital in evaluation of emergency room patients complaining of chest pain. POC assays ombining CK-MB and myoglobin have better sensitivity and specificity in diagnosis of myocardial infraction and may also offer earliest identification of myocardial injury. Troponin T assays are the most utilized in POC settings along with Troponin I.
"Myocardial Necrosis and Ischemia to Contribute Highest Revenue"
Consistent increase in sedentary lifestyle, overall stress levels, changes in dietary habits, smoking and alcohol use, and growing geriatric population are the key factors that have resulted in growing incidence of myocardial infraction. The two well-known biomarkers used for diagnosis of acute myocardial infraction/necrosis are CK-MB and cardiac troponin. Since 2000, cardiac troponin has successfully replaced CK-MB as the marker of choice for diagnosis of myocardial infraction. Quick identification of acute myocardial infraction is deemed to be mandatory for initiation of effective treatment and better prognosis. Troponin T is present in the bound form to the contractile myocardial cells, and presents dual release of the cytoplasmic component. Troponin I also is extremely specific to the cardiac muscle. Their absolute specificity makes troponin I & T the ideal markers for myocardial necrosis.
"Asia Pacific to Have Significant Market Opportunities in Store"
Currently, North America leads the global cardiac markers market, globally. High incidence of cardiac emergencies, significantly large proportion of population leading sedentary lifestyle along with high risk dietary profile are the basic factors supporting the dominance of North America market. Additionally, the availability of both POC and laboratory-based cardiac marker tests is also widespread in the region, along with supportive high awareness in the general population. However, Asia Pacific is anticipated to progress at the fastest CAGR during the forecast period. Large population pool, along with greater adoption of high sugar and fat diets are contributing to increasing prevalence of chronic heart diseases. This as therefore led to growth in adoption of advanced diagnostic tools for management of such patient pool. Additionally, as the medical tourism market in the region is flourishing, the demand for advanced diagnostic solutions for cardiac diseases is also on the growth. This has resulted in increased penetration of global market giants to augment their market penetration activities in the Asia Pacific market.
Historical & Forecast Period
This research report presents the analysis of each considered segment for the period from 2016 to 2026, having 2017 as the base year for estimations. Compounded annual growth rates (CAGRs) for each segment are calculated for the forecast period from 2018 to 2026.
The qualitative analysis presented in this report gives insights on the determinant market dynamics of the cardiac markers industry. Such market dynamics are classified as market drivers, challenges and opportunities. The major market players involved in cardiac biomarkers industry are also assessed in terms of their business overview, product portfolio, financial status and key developments. The prominent market players profiled in this report are Abbott Laboratories, Inc., Roche Diagnostics Limited, Danaher Corporation, Bio-Rad Laboratories, Inc., Becton, Dickinson and Company, LSI Medience Corporation, Beckman Coulter, Inc. (Danaher Corporation),bioMerieux SA, Ortho Clinical Diagnostics, Siemens Healthcare Diagnostics, Randox Laboratories Ltd., Tosoh Bioscience and Quest Diagnostics, Inc.
Chapter 1. Preface
1.1. Report Description
1.1.1. Study Purpose
1.1.2. Target Audience
1.1.3. USP and Key Offerings
1.2. Research Scope
1.3. Research Methodology
1.3.1. Phase I – Secondary Research
1.3.2. Phase II – Primary Research
1.3.3. Phase III – Expert Panel Review
1.3.4. Assumptions
1.4. Market Segmentation
Chapter 2. Executive Summary
2.1. Global CM Market Portraiture
2.2. Global CM Market, by Type, 2017 (US$ Mn)
2.3. Global CM Market, by Product, 2017 (US$ Mn)
2.4. Global CM Market, by Condition, 2017 (US$ Mn)
2.5. Global CM Market, by Testing Type, 2017 (US$ Mn)
2.6. Global CM Market, by Geography, 2017 (US$ Mn)
Chapter 3. Global Cardiac Markers (CM) Market: Dynamics and Future Outlook
3.1. Overview
3.2. Drivers
3.3. Challenges
3.4. Opportunities
3.5. Attractive Investment Proposition, by Geography, 2017
3.6. Competitive Analysis: Global CM Market, by Key Players, 2017
Chapter 4. Global Cardiac Markers (CM) Market, by Type, 2016 - 2026 (US$ Mn)
4.1. Overview
4.2. Cardiac troponin I and T
4.3. CK-MB
4.4. Myoglobin
4.5. B type natriuretic peptide (BNP) and NT-proBNP
4.6. hs-C-Reactive Protein (hs-CRP)
4.7. Myeloperoxidase (MPD)
4.8. Ischaemia Modified Albumin
4.9. Others
Chapter 5. Global Cardiac Markers (CM) Market, by Product, 2016 - 2026 (US$ Mn)
5.1. Overview
5.2. Instruments
5.2.1. Chemiluminescence
5.2.2. Immunofluorescence
5.2.3. Immunochromatography
5.2.4. ELISA
5.3. Reagents and Kits
Chapter 6. Global Cardiac Markers (CM) Market, by Condition, 2016 - 2026 (US$ Mn)
6.1. Overview
6.2. Plaque Formation
6.3. Plaque Instability/ Rupture
6.4. Myocardial Necrosis and Ischemia
6.5. Heart Failure
Chapter 7. Global Cardiac Markers (CM) Market, by Testing Type, 2016 - 2026 (US$ Mn)
7.1. Overview
7.2. Laboratory Testing
7.3. Point-of-Care Testing
Chapter 8. Global Cardiac Markers (CM) Market, by Geography, 2016 – 2026 (US$ Mn)
8.1. Overview
8.1.1. North America CM Market, 2016 - 2026 (US$ Mn)
8.1.2. North America CM Market, by Type, 2016 - 2026 (US$ Mn)
8.1.3. North America CM Market, by Product, 2016 - 2026 (US$ Mn)
8.1.4. North America CM Market, by Condition, 2016 - 2026 (US$ Mn)
8.1.5. North America CM Market, by Testing Type, 2016 - 2026 (US$ Mn)
8.1.6. North America CM Market, by Country, 2016 – 2026 (US$ Mn)
8.1.6.1. U.S.
8.1.6.2. Canada
8.2. Europe CM Market, 2016 – 2026 (US$ Mn)
8.2.1. Europe CM Market, by Type, 2016 - 2026 (US$ Mn)
8.2.2. Europe CM Market, by Product, 2016 - 2026 (US$ Mn)
8.2.3. Europe CM Market, by Condition, 2016 - 2026 (US$ Mn)
8.2.4. Europe CM Market, by Testing Type, 2016 - 2026 (US$ Mn)
8.2.5. Europe CM Market, by Country/Region, 2016 – 2026 (US$ Mn)
8.2.5.1. U.K.
8.2.5.2. Germany
8.2.5.3. Rest of Europe
8.3. Asia Pacific CM Market, 2016 – 2026 (US$ Mn)
8.3.1. Asia Pacific CM Market, by Type, 2016 - 2026 (US$ Mn)
8.3.2. Asia Pacific CM Market, by Product, 2016 - 2026 (US$ Mn)
8.3.3. Asia Pacific CM Market, by Condition, 2016 - 2026 (US$ Mn)
8.3.4. Asia Pacific CM Market, by Testing Type, 2016 - 2026 (US$ Mn)
8.3.5. Asia Pacific CM Market, by Country/Region, 2016 – 2026 (US$ Mn)
8.3.5.1. China
8.3.5.2. Japan
8.3.5.3. Rest of Asia Pacific
8.4. Latin America CM Market, 2016 – 2026 (US$ Mn)
8.4.1. Latin America CM Market, by Type, 2016 - 2026 (US$ Mn)
8.4.2. Latin America CM Market, by Condition, 2016 - 2026 (US$ Mn)
8.4.3. Latin America CM Market, by Product, 2016 - 2026 (US$ Mn)
8.4.4. Latin America CM Market, by Testing Type, 2016 - 2026 (US$ Mn)
8.4.5. Latin America CM Market, by Country/Region, 2016 – 2026 (US$ Mn)
8.4.5.1. Brazil
8.4.5.2. Mexico
8.4.5.3. Rest of Latin America
8.5. Middle East & Africa CM Market, 2016 – 2026 (US$ Mn)
8.5.1. Middle East & Africa CM Market, by Type, 2016 - 2026 (US$ Mn)
8.5.2. Middle East & Africa CM Market, by Product, 2016 - 2026 (US$ Mn)
8.5.3. Middle East & Africa CM Market, by Condition, 2016 - 2026 (US$ Mn)
8.5.4. Middle East & Africa CM Market, by Testing Type, 2016 - 2026 (US$ Mn)
8.5.5. Middle East & Africa CM Market, by Region, 2016 – 2026 (US$ Mn)
8.5.5.1. GCC
8.5.5.2. Rest of Middle East & Africa
Chapter 9. Company Profiles
9.1. Abbott Laboratories, Inc.
9.1.1. Business Description
9.1.2. Financial Information (Subject to Data Availability)
9.1.3. Product Portfolio
9.1.4. Key Developments
9.2. Roche Diagnostics Limited
9.3. Danaher Corporation
9.4. Bio-Rad Laboratories, Inc.
9.5. Becton, Dickinson and Company
9.6. LSI Medience Corporation
9.7. Beckman Coulter, Inc. (Danaher Corporation)
9.8. bioMerieux SA
9.9. Ortho Clinical Diagnostics
9.10. Siemens Healthcare Diagnostics
9.11. Randox Laboratories Ltd.
9.12. Tosoh Bioscience
9.13. Quest Diagnostics, Inc.
* CM - Cardiac Markers
TABLE 1 Global Cardiac Markers (CM) Market Portraiture
TABLE 2 Global CM Market, by Type, 2016 – 2026 (US$ Mn)
TABLE 3 Global CM Market, by Product, 2016 – 2026 (US$ Mn)
TABLE 4 Global Cardiac Marker Instruments Market, by Type, 2016 – 2026 (US$ Mn)
TABLE 5 Global CM Market, by Condition, 2016 – 2026 (US$ Mn)
TABLE 6 Global CM Market, by Testing Type, 2016 – 2026 (US$ Mn)
TABLE 7 Global CM Market, by Geography, 2016 – 2026 (US$ Mn)
TABLE 8 North America CM Market, by Type, 2016 – 2026 (US$ Mn)
TABLE 9 North America CM Market, by Product, 2016 – 2026 (US$ Mn)
TABLE 10 North America CM Market, by Condition, 2016 – 2026 (US$ Mn)
TABLE 11 North America CM Market, by Testing Type, 2016 – 2026 (US$ Mn)
TABLE 12 North America CM Market, by Country, 2016 – 2026 (US$ Mn)
TABLE 13 Europe CM Market, by Type, 2016 – 2026 (US$ Mn)
TABLE 14 Europe CM Market, by Product, 2016 – 2026 (US$ Mn)
TABLE 15 Europe CM Market, by Condition, 2016 – 2026 (US$ Mn)
TABLE 16 Europe CM Market, by Testing Type, 2016 – 2026 (US$ Mn)
TABLE 17 Europe CM Market, by Country/Region, 2016 – 2026 (US$ Mn)
TABLE 18 Asia Pacific CM Market, by Type, 2016 – 2026 (US$ Mn)
TABLE 19 Asia Pacific CM Market, by Product, 2016 – 2026 (US$ Mn)
TABLE 20 Asia Pacific CM Market, by Condition, 2016 – 2026 (US$ Mn)
TABLE 21 Asia Pacific CM Market, by Testing Type, 2016 – 2026 (US$ Mn)
TABLE 22 Asia Pacific CM Market, by Country/Region, 2016 – 2026 (US$ Mn)
TABLE 23 Latin America CM Market, by Type, 2016 – 2026 (US$ Mn)
TABLE 24 Latin America CM Market, by Product, 2016 – 2026 (US$ Mn
TABLE 25 Latin America CM Market, by Condition, 2016 – 2026 (US$ Mn)
TABLE 26 Latin America CM Market, by Testing Type, 2016 – 2026 (US$ Mn)
TABLE 27 Latin America CM Market, by Country/Region, 2016 – 2026 (US$ Mn)
TABLE 28 Middle East and Africa CM Market, by Type, 2016 – 2026 (US$ Mn)
TABLE 29 Middle East and Africa CM Market, by Product, 2016 – 2026 (US$ Mn)
TABLE 30 Middle East and Africa CM Market, by Condition, 2016 – 2026 (US$ Mn)
TABLE 31 Middle East and Africa CM Market, by Testing Type, 2016 – 2026 (US$ Mn)
TABLE 32 Middle East and Africa CM Market, by Region, 2016 – 2026 (US$ Mn)
TABLE 33 GE Healthcare: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 34 Abbott Laboratories, Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 35 Roche Diagnostics Limited: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 36 Danaher Corporation: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 37 Bio-Rad Laboratories, Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 38 Becton, Dickinson and Company: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 39 LSI Medience Corporation: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 40 Beckman Coulter, Inc. (Danaher Corporation): Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 41 bioMerieux SA: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 42 Ortho Clinical Diagnostics: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 43 Siemens Healthcare Diagnostics: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 44 Randox Laboratories Ltd.: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 45 Tosoh Bioscience: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 46 Quest Diagnostics, Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
FIG 1. Cardiac Markers (CM) Market: Research Methodology
FIG 2. CM Market Segmentation
FIG 3. Global CM Market, by Type, 2017 (US$ Mn)
FIG 4. Global CM Market, by Product, 2017 (US$ Mn)
FIG 5. Global CM Market, by Condition, 2017 (US$ Mn)
FIG 6. Global CM Market, by Testing Type, 2017 (US$ Mn)
FIG 7. Global CM Market, by Geography, 2017 (US$ Mn)
FIG 8. Attractive Investment Proposition, by Geography, 2017
FIG 9. Competitive Analysis: Global CM Market, by Key Players, 2017
FIG 10. Global Cardiac troponin I and T CM Market, 2016 - 2026 (US$ Mn)
FIG 11. Global CK-MB CM Market, 2016 - 2026 (US$ Mn)
FIG 12. Global Myoglobin CM Market, 2016 - 2026 (US$ Mn)
FIG 13. Global B type natriuretic peptide (BNP) and NT-proBNP CM Market, 2016 - 2026 (US$ Mn)
FIG 14. Global hs-C-Reactive Protein (hs-CRP) CM Market, 2016 - 2026 (US$ Mn)
FIG 15. Global Myeloperoxidase (MPD) CM Market, 2016 - 2026 (US$ Mn)
FIG 16. Global Ischaemia Modified Albumin CM Market, 2016 - 2026 (US$ Mn)
FIG 17. Global Other CM Market, 2016 - 2026 (US$ Mn)
FIG 18. Global Chemiluminescence Cardiac Marker Instruments Market, 2016 - 2026 (US$ Mn)
FIG 19. Global Immunofluorescence Cardiac Marker Instruments Market, 2016 - 2026 (US$ Mn)
FIG 20. Global Immunochromatography Cardiac Marker Instruments Market, 2016 - 2026 (US$ Mn)
FIG 21. Global ELISA Cardiac Marker Instruments Market, 2016 - 2026 (US$ Mn)
FIG 22. Global Cardiac Marker Reagents and Kits Market, 2016 - 2026 (US$ Mn)
FIG 23. Global CM Market for Plaque Formation, 2016 - 2026 (US$ Mn)
FIG 24. Global CM Market for Plaque Instability/ Rupture, 2016 - 2026 (US$ Mn)
FIG 25. Global CM Market for Myocardial Necrosis and Ischemia, 2016 - 2026 (US$ Mn)
FIG 26. Global CM Market for Heart Failure, 2016 - 2026 (US$ Mn)
FIG 27. Global CM Market in Laboratory Testing, 2016 - 2026 (US$ Mn)
FIG 28. Global CM Market in Point-of-Care Testing, 2016 - 2026 (US$ Mn)
FIG 29. U.S. CM Market, 2016 - 2026 (US$ Mn)
FIG 30. Canada CM Market, 2016 - 2026 (US$ Mn)
FIG 31. U.K. CM Market, 2016 - 2026 (US$ Mn)
FIG 32. Germany CM Market, 2016 - 2026 (US$ Mn)
FIG 33. Rest of Europe CM Market, 2016 - 2026 (US$ Mn)
FIG 34. China CM Market, 2016 - 2026 (US$ Mn)
FIG 35. Japan CM Market, 2016 - 2026 (US$ Mn)
FIG 36. India CM Market, 2016 - 2026 (US$ Mn)
FIG 37. Rest of Asia Pacific CM Market, 2016 - 2026 (US$ Mn)
FIG 38. Brazil CM Market, 2016 - 2026 (US$ Mn)
FIG 39. Mexico CM Market, 2016 - 2026 (US$ Mn)
FIG 40. Rest of Latin America CM Market, 2016 - 2026 (US$ Mn)
FIG 41. GCC CM Market, 2016 - 2026 (US$ Mn)
FIG 42. Rest of Middle East and Africa CM Market, 2016 - 2026 (US$ Mn)