Cell Free Protein Expression Market By Product Type (E.Coli Cell-Free Protein Expression System, Rabbit Reticulocytes Cell-Free Protein Expression System, Wheat Germ Cell-Free Protein Expression System, Insect Cells Cell-Free Protein Expression System & Others), By Application Type (Enzyme Engineering, Protein Labeling, Protein-Protein Interaction & Others), By Expression Mode Type(Continuous Flow Expression, Batch Expression) - Growth, Share, Opportunities & Competitive Analysis, 2017-2025

Published By: Brisk Insights | Published On: Apr 18, 2022

 

For decades, cell free protein expression method is being used for analysis of proteins. The most commonly used lysate include wheat germ or reticulocyte lysates. There is tremendous improvement in E. coli and wheat germ derived cell-free systems. Further interest of biotechnology and biopharmaceutical companies (Qiagen, Roche, Novagen, Invitrogen) in commercialization of these tools have led to growth of cell-free protein expression market. Surge in the research and development activities, increased interest in genomics and proteomics and demand for biologics are some of the key factors propelling the growth of cell-free protein expression market. However some hindrance while using cell-free systems is the low yield of target protein.

 

The report titled “Cell Free Protein Expression Market - Growth, Future Prospects and Competitive Analysis, 2017–2025” offers strategic insights into the overall cell free protein expression market along with the market size and estimates for the duration 2015 to 2025. The said research study covers in-depth analysis of multiple market segments based on type of product, application, expression mode and different geographies. The product types studied for analyzing the overall global cell free protein expression market are majorly segmented into E. coli cell-free protein expression system, rabbit reticulocytes cell-free protein expression system, wheat germ cell-free protein expression system, insect cells cell-free protein expression system, mammalian cell-free protein expression system, and consumables. The global cell-free protein expression market is segmented by application type into polyurethane, polyurethane/polycarbonate and silicone. It also segmented by expression mode into continuous flow expression and batch expression.

 

Geographically, the global cell free protein expression market is studied for the following regional markets:

 

  • North America
    • U.S.
    • Canada
  • Europe
    • U.K.
    • Germany
    • Rest of Europe
  • Asia-Pacific
    • China
    • Japan
    • Rest of Asia Pacific
  • Latin America
    • Mexico
    • Brazil
    • Rest of LATAM
  • Middle East and Africa
    • UAE
    • Saudi Arabia
    • South Africa
    • Rest of Middle East and Africa

 

Market size and forecast for these regional and country level markets are presented in this study for the period 2015-2025. Market growth rates for the forecast period 2017-2025 are also included in this report, considering 2016 as the base year.

 

Along with quantitative information, qualitative information sets and assessment tools are provided in this study for better analysis of the overall market scenario and future prospects. Information such as market inclination insights and drivers, challenges and opportunities assists the readers for understanding the ongoing trends in the global cell free protein expression market. Tools such as market positioning of key players and attractive investment proposition provide the readers with insights on the competitive scenario of the global cell free protein expression market. This report concludes with company profiles section that highlights major information about the key players engaged in global cell free protein expression market. In-depth competitive environment analysis and historical (2015) market size data are also provided in the report.

 

Based on the type of product, the global cell free protein expression market is segmented as follows:

 

  • E.coli Cell-free Protein Expression System
  • Rabbit Reticulocytes Cell-free Protein Expression System
  • Wheat Germ Cell-free Protein Expression System
  • Insect Cells Cell-free Protein Expression System
  • Mammalian Cell-free Protein Expression System
  • Consumables
  • Labelling Tags
  • Vectors

 

E. coli lysate is the most simple and well established cell free protein expression system for high yield production of prokaryotic proteins. In eukaryotic system most widely used is rabbit reticulocyte lysate (RRL) cell free protein expression system. It is more efficient and reduces the probability of error when compared with E. coli system. White germ lysate is another eukaryotic expression system, which is popularly used and yields higher output compared to other eukaryotic system and used for large size protein expression method. Insect cell lysate is also used for large-size protein expression. Mammalian cell free protein expression method is anticipated to the be the most fast growing segment of cell protein expression market due to most preferred option for production of human protein. Rising demand for biologics and proteomics research and its application in human drug discovery is the driving factor for the growth mammalian cell free protein expression system market.

 

Based on the type of application, the global cell free protein expression market is segmented as follows:

 

  • Enzyme Engineering
  • Protein Labeling
  • Protein-Protein interaction
  • Protein Purification

 

Currently, cell free protein expression is one of the most lucrative market with high adoption rate by biopharmaceutical and biotechnological industry. It is being widely used in high-throughput functional proteomics and genomics. Protein- protein interaction segments occupies the largest share of the cell free protein market expression. There is also significant growth observed in the research and development in protein production and generation of protein libraries contributing to the fast growth of protein- protein interaction segment.

 

Based on the type of expression mode, the global cell free protein expression market is segmented as follows:

 

  • Continuous flow Expression
  • Batch Expression

 

Conventionally, batch expression was used for synthesis of target protein, as it is easy to handle, fast and reliable source for protein synthesis. Novel technique, continuous flow expression system is used for synthesis of both prokaryotic and eukaryotic proteins. Continuous-Exchange Cell-free (CECF) protein synthesis system yield better protein when compared with batch reaction. Thus, continuous flow expression system accounts for large share of cell free protein expression market, and it expected to grow in the forecast period.

 

For the purpose of this study, the global cell free protein expression market is geographically categorized into:

 

  • North America (U.S., Canada)
  • Europe (UK, Germany and Rest of Europe)
  • Asia Pacific (China, Japan and Rest of Asia)
  • Latin America (LATAM)
  • Middle East and Africa (MEA)

 

Cell-free protein expression has emerged as powerful novel technology that show continuous improvement and is ever expanding. Due to advance in CFPE, it possible from small scale to manufacturing scale protein synthesis, has inspired application in genomics and structural biology, personalized medicine and proteomic industrial application.At present, North America dominates the global cell free protein expression market followed by the Europe market. Huge investment in research and development, and rising demand of protein synthesis are the main drivers for the growth of cell protein fusion market. North America and Europe region occupies more than half of the global cell free protein expression market. Asia-Pacific is anticipated to be the fastest growing cell free protein expression market. Rise in research and development activities, increase in funding by government and biopharmaceutical & biotechnology companies coupled with surged  demand of protein synthesis is the reason for growth in  emerging market such as China and India.

 

Chapter 1 Preface


1.1 Report Description
1.1.1 Purpose of the Report
1.1.2 Target Audience
1.1.3 USP and Key Offerings
1.2 Research Scope
1.3 Research Methodology
1.3.1 Phase I – Secondary Research
1.3.2 Phase II – Primary Research
1.3.3 Phase III – Expert Panel Review
1.3.4 Assumptions

 

Chapter 2 Executive Summary


2.1 Global Cell-free Protein Expression Market Portraiture
2.2 Global Cell-free Protein Expression Market Share, by Product type, 2016 (US$)
2.3 Global Cell-free Protein Expression Market Share, by Application type, 2016  (US$)
2.4 Global Cell-free Protein Expression Market Share, by Expression mode type, 2016  (US$)
2.5 Global Cell-free Protein Expression Market, by Geography, 2016 (Value %)

 

Chapter 3 Global Cell-free Protein Expression Market Analysis


3.1 Global Cell-free Protein Expression Market Overview
3.2 Market Dynamics
3.2.1 Market Drivers
3.2.2 Challenges
3.2.3 Opportunities
3.3 Attractive Investment Proposition
3.4 Competitive Landscape of Key Players in Cell-free Protein Expression Market

 

Chapter 4 Global Cell-free Protein Expression Market Analysis, by Product Type, 2015-2025 (US$ Mn)


4.1 Introduction
4.2 E.coli Cell-free Protein Expression System
4.3 Rabbit Reticulocytes Cell-free Protein Expression System
4.4 Wheat Germ Cell-free Protein Expression System
4.5 Insect Cells Cell-free Protein Expression System
4.6 Mammalian Cell-free Protein Expression System
4.7 Consumables
4.8 Labelling Tags
4.9 Vectors

 

Chapter 5 Global Cell-free Protein Expression Market Analysis, by Application Type, 2015-2025 (US$ Mn)


5.1 Introduction
5.2 Enzyme Engineering
5.3 Protein Labeling
5.4 Protein-Protein interaction
5.5 Protein Purification

 

Chapter 6 Global Cell-free Protein Expression Market Analysis, by Expression mode Type, 2015-2025 (US$ Mn)


6.1 Introduction
6.2 Continuous flow Expression
6.3 Batch Expression

 

Chapter 7 Global Cell-free Protein Expression Market, By Geography, 2015-2025 (US$ Mn)


7.1 Preface
7.2 North America (U.S. & Canada)
7.3 Europe (U.K., Germany & Rest of Europe)
7.4 Asia Pacific (China, Japan, and Rest of APAC)
7.5 Latin America (Brazil, Mexico and Rest of LATAM)
7.6 Middle East and Africa (UAE, Saudi Arabia, South Africa)

 

Chapter 8 Company Profiles


8.1 Bioneer Corporation
8.2 Biotechrabbit GmbH,
8.3 CellFree Sciences Co.
8.4 Cube Biotech GmbH
8.5 GeneCopoeia, Inc.
8.6 Jena Bioscience GmbH
8.7 New England Biolabs
8.8 Promega Corporation
8.9 Takara Bio,Inc
8.10 Thermo Fisher Scientific

TABLE 1 Global Cell-free Protein Expression Market, By Product Type 2015-2025 (US$ Mn)
TABLE 2 Global Cell-free Protein Expression Market, By Application Type 2015-2025 (US$ Mn)
TABLE 3 Global Cell-free Protein Expression Market, By Expression mode Type 2015-2025 (US$ Mn)
TABLE 4 Global Cell-free Protein Expression Market, by Geography, 2015 – 2025 (US$ Mn)
TABLE 5 North America Cell-free Protein Expression Market, by Country, 2015 – 2025 (US$ Mn)
TABLE 6 Europe Cell-free Protein Expression Market, by Country, 2015 – 2025 (US$ Mn)
TABLE 7 Asia-Pacific Cell-free Protein Expression Market, by Country, 2015 – 2025 (US$ Mn)
TABLE 8 Bioneer Corporation: Company Snapshot (Business Description; Financial Performance; Product Portfolio; News Coverage)
TABLE 9 Biotechrabbit GmbH,: Company Snapshot (Business Description; Financial Performance; Product Portfolio; News Coverage)
TABLE 10 CellFree Sciences Co.: Company Snapshot (Business Description; Financial Performance; Product Portfolio; News Coverage)
TABLE 11 Cube Biotech GmbH: Company Snapshot (Business Description; Financial Performance; Product Portfolio; News Coverage)
TABLE 12 GeneCopoeia, Inc.: Company Snapshot (Business Description; Financial Performance; Product Position Portfolio; News Coverage)
TABLE 13 Jena Bioscience GmbH: Company Snapshot (Business Description; Financial Performance; Product Portfolio; News Coverage)
TABLE 14 New England Biolabs: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 15 Promega Corporation: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 16 Takara Bio,Inc: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 17 Thermo Fisher Scientific: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)

FIG. 1 Global Cell-free Protein Expression Market: Research Methodology
FIG. 2 Global Cell-free Protein Expression Market Share, by Product type, 2016 (US$)
FIG. 3 Global Cell-free Protein Expression Market Share, by Application type, 2016 (US$)
FIG. 4 Global Cell-free Protein Expression Market Share, by Expression mode type, 2016 (US$)
FIG. 5 Global Cell-free Protein Expression Market, by Geography, 2016 (Value %)
FIG. 6 Attractive Investment Proposition: Global Cell-free Protein Expression Market, by Geography
FIG. 7 Competitive Analysis: Key Players in Global Cell-free Protein Expression Market
FIG. 8 Global E.coli Cell-free Protein Expression System Market, 2015 – 2025 (US$ Mn)
FIG. 9 Global Rabbit Reticulocytes Cell-free Protein Expression System Market, 2015 – 2025 (US$ Mn)
FIG. 10 Global Wheat Germ Cell-free Protein Expression System Market, 2015 – 2025 (US$ Mn)
FIG. 11 Global Insect Cells Cell-free Protein Expression System Market, 2015 – 2025 (US$ Mn)
FIG. 12 Global Mammalian Cell-free Protein Expression System Market, 2015 – 2025 (US$ Mn)
FIG. 13 Global Consumables Market, 2015 – 2025 (US$ Mn)
FIG. 14 Global Labelling Tags Market, 2015 – 2025 (US$ Mn)
FIG. 15 Global Vectors Market, 2015 – 2025 (US$ Mn)
FIG. 16 Global Enzyme Engineering Market, 2015 – 2025 (US$ Mn)
FIG. 17 Global Protein Labeling Market, 2015 – 2025 (US$ Mn)
FIG. 18 Global Protein-Protein interaction Market, 2015 – 2025 (US$ Mn)
FIG. 19 Global Protein Purification Market, 2015 – 2025 (US$ Mn)
FIG. 20 Global Continuous flow Expression Market, 2015 – 2025 (US$ Mn)
FIG. 21 Global Batch Expression Market, 2015 – 2025 (US$ Mn)
FIG. 22 Latin America Cell-free Protein Expression Market, 2015 – 2025 (US$ Mn)
FIG. 23 Middle East & Africa Cell-free Protein Expression Market, 2015 – 2025 (US$ Mn)

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