Industry Outlook
Devic’s syndrome (Neuromyelitis optica) treatment accounted for a market value of US$ 156.8 Mn in 2018 and projected to grow at a CAGR of 12.0% during the forecast period from 2019 to 2027. Devic's disease or neuromyelitis optica is an autoimmune disease in which antibodies and immune system cells mainly damage the optic nerves and the spinal cord, but in a few cases affect the brain. The injury to optical nerves leads to inflammation and soreness leading to vision loss and pain; the injury to the spinal cord leads to paralysis in the arms or legs, loss of sensation, and problems with bladder & bowel function. The key factors responsible for growth of global Devic’s syndrome treatment market are rising awareness & prevalence related to orphan diseases, recent launch of first-target specific drug Soliris (Eculizumab) and strong drug pipeline expected to provide significant growth in the market.
"Soliris (Eculizumab) will aid the significant growth of Devic’s Syndrome treatment market throughout the forecast period"
Soliris (Eculizumab) is a terminal complement inhibitor owned by Alexion. Soliris works by specifically preventing activation of particular proteins in the complement system (C5a and C5b), which play a role in the treatment of Devic’s syndrome. Patients suffering with Devic’s syndrome possess AQP4 antibody-positive, the body’s immune system can turn against itself to produce autoantibodies against AQP4. Activation of anti-AQP4 autoantibodies leads to damage of vital cells in the CNS assisting further demyelination and death of neurons, primarily in the optic nerve and spinal cord. There are three promising molecules in Devic’s syndrome treatment pipeline such as Satralizumab – Phase 3 (Hoffmann-La Roche/ Chugai Pharmaceutical), MEDI-551- Phase 2/3 (MedImmune LLC), and RC18 – Phase 3 (RemeGen, Ltd.). Chugai Pharmaceutical launched Phase 2 results related to Satralizumab on 15 October 2018; it is an investigational humanized anti-IL-6 receptor recycling monoclonal antibody for the treatment of neuromyelitis optica spectrum disorder (NMOSD).
"North America dominated the overall global market specifically due to recent drug approval, promising drugs in pipeline, and developed diagnostic landscape"
In 2018, North America dominated the market and anticipated to retain its position throughout the forecast period due to high awareness related to orphan diseases, rising requirement for target-specific molecules to treat Devic’s Syndrome, and easy adaptability & accessibility for newly launched drug. According to National Multiple Sclerosis Society, there are around 4,000 people suffering with Devic’s syndrome in the United States with majority of women population. Asia Pacific will grow during the forecast period from 2019 to 2027, due to increasing awareness related to Devic’s Syndrome assisting the rise in diagnosis & treatment rate in patients suffering with rare diseases.
Historical & Forecast Period
The Devic’s Syndrome treatment market analyzed considering current market trends for base year 2018 and based on future trends CAGRs calculated for the forecast period from 2019 to 2027.
This report comprises in-depth information related to the Devic’s Syndrome treatment market along with major factors affecting or assisting market such as opportunities, drivers, & restraints. A descriptive data covering market drivers, challenges & opportunities provided specifically for country-level and regional segmentation. This report covered detailed info related to the global Devic’s syndrome treatment market segmented based on drug type, and geography. The report also include pipeline analysis of upcoming drugs, competitive analysis of the major companies present in Devic’s Syndrome treatment market including detailed data related to the competitive landscape of the market and the recent market strategies & products pipeline.
ATTRIBUTE | DETAILS |
---|---|
Research Period | 2017-2027 |
Base Year | 2018 |
Forecast Period | 2019-2027 |
Historical Year | 2017 |
Unit | USD Million |
Segmentation |
Type of Drugs Segment (2017–2027; US$ Mn) |
Pipeline Analysis (2017–2027; US$ Mn) |
|
Geography Segment (2017–2027; US$ Mn) |
The major companies involved in the Devic’s Syndrome treatment industry studied based on financial data, product portfolio, current press releases, and key market strategies. This report also covers attractive investment proposition analyzed based on exclusive geographical PESTEL analysis. Major companies included in the report are Alexion Pharmaceuticals, Inc., Teva Pharmaceuticals, Fresenius Kabi AG, Pharmacia & Upjohn (a subsidary of Pfizer), Mylan Pharmaceuticals, Inc., Chugai Pharmaceutical, MedImmune LLC, and RemeGen, Ltd. among others.
Chapter 1. Preface
1.1. Report Scope and Description
1.1.1. Study Purpose
1.1.2. Target Audience
1.1.3. USP and Key Offerings
1.2. Research Methodology
1.2.1. Phase I-Secondary Research
1.2.2. Phase II-Primary Research
1.2.3. Phase III-Expert Panel Review
1.2.4. Assumptions
1.2.5. Approach Adopted
Chapter 2. Executive Summary
2.1. Global DST Market Portraiture
2.2. Global DST Market, by Type of Drug, 2018 (US$ Mn)
2.3. Global DST Market, by Geography, 2018 Vs 2027 (Value %)
Chapter 3. Global Devic’s Syndrome Treatment (DST) Market: Market Dynamics and Future Outlook
3.1. Market Overview
3.2. Drivers
3.3. Challenges
3.4. Opportunities
3.5. Attractive Investment Proposition, by Geography, 2018
3.6. Competitive Landscape
3.6.1. Competitive Landscape, by Key Players, 2018
Chapter 4. Global Devic’s Syndrome Treatment (DST) Market, by Type of Drugs, 2017 – 2027 (US$ Mn)
4.1. Overview
4.2. Eculizumab
4.3. Methylprednisolone
4.4. Azathioprine
4.5. Mycophenolate Mofetil
4.6. Rituximab
Chapter 5. Global Devic’s Syndrome Treatment (DST) Market, Pipeline Analysis
5.1. Overview
5.2. Satralizumab – Phase III (Hoffmann-La Roche/ Chugai Pharmaceutical)
5.3. MEDI-551 – Phase II/III (MedImmune LLC)
5.4. RC18 – Phase III (RemeGen, Ltd.)
Chapter 6. Global Devic’s Syndrome Treatment (DST) Market, by Geography, 2017 – 2027 (US$ Mn)
6.1. Overview
6.2. North America DST Market Analysis, 2017 – 2027
6.2.1. North America DST Market, by Type of Drugs, 2017–2027 (US$ Mn)
6.2.2. North America DST Market, by Country, 2017 – 2027 (US$ Mn)
6.2.2.1. U.S.
6.2.2.2. Canada
6.3. Europe DST Market Analysis, 2017 – 2027
6.3.1. Europe DST Market, by Type of Drugs, 2017–2027 (US$ Mn)
6.3.2. Europe DST Market, by Country, 2017 – 2027 (US$ Mn)
6.3.2.1. U.K.
6.3.2.2. Germany
6.3.2.3. Rest of Europe
6.4. Asia Pacific DST Market Analysis, 2017 – 2027
6.4.1. Asia Pacific DST Market, by Type of Drugs, 2017–2027 (US$ Mn)
6.4.2. Asia Pacific DST Market, by Country, 2017 – 2027 (US$ Mn)
6.4.2.1. Japan
6.4.2.2. China
6.4.2.3. Rest of APAC
6.5. Latin America DST Market Analysis, 2017 – 2027
6.5.1. Latin America DST Market, by Type of Drugs, 2017–2027 (US$ Mn)
6.5.2. Latin America DST Market, by Country, 2017 – 2027 (US$ Mn)
6.5.2.1. Brazil
6.5.2.2. Mexico
6.5.2.3. Rest of Latin America
6.6. Middle East & Africa (MEA) DST Market Analysis, 2017 – 2027
6.6.1. Middle East & Africa DST Market, by Type of Drugs, 2017–2027 (US$ Mn)
6.6.2. MEA DST Market, by Region, 2017 – 2027 (US$ Mn)
6.6.2.1. GCC
6.6.2.2. Rest of MEA
Chapter 7. Company Profiles
7.1. Alexion Pharmaceuticals, Inc.
7.1.1. Business Description
7.1.2. Financial Information (Subject to data availability)
7.1.3. Product Portfolio
7.1.4. Key Developments
7.2. Teva Pharmaceuticals
7.3. Fresenius Kabi AG
7.4. Pharmacia & Upjohn (a subsidary of Pfizer)
7.5. Lupin Ltd.
7.6. Sagent Pharmaceuticals, Inc.
7.7. Zydus Pharmaceuticals, Inc.
7.8. Sandoz Inc. (a subsidiary of Novartis)
7.9. Alkem Laboratories Ltd.
7.10. Mylan Pharmaceuticals, Inc.
7.11. Hoffmann-La Roche/ Chugai Pharmaceutical
7.12. MedImmune LLC
7.13. RemeGen, Ltd.
* Here we are using DST as a short form of Devic’s Syndrome Treatment
TABLE 1 Global Devic’s Syndrome Treatment (DST) Market, by Type of Drugs, 2017 – 2027 (US$ Mn)
TABLE 2 North America DST Market, by Type of Drugs, 2017 – 2027 (US$ Mn)
TABLE 3 North America DST Market, by Country/Region, 2017 – 2027 (US$ Mn)
TABLE 4 Europe DST Market, by Type of Drugs, 2017 – 2027 (US$ Mn)
TABLE 5 Europe DST Market, by Country/Region, 2017 – 2027 (US$ Mn)
TABLE 6 Asia Pacific DST Market, by Type of Drugs, 2017 – 2027 (US$ Mn)
TABLE 7 Asia Pacific DST Market, by Country/Region, 2017 – 2027 (US$ Mn)
TABLE 8 Latin America DST Market, by Type of Drugs, 2017 – 2027 (US$ Mn)
TABLE 9 Latin America DST Market, by Country/Region, 2017 – 2027 (US$ Mn)
TABLE 10 Middle East & Africa DST Market, by Type of Drugs, 2017 – 2027 (US$ Mn)
TABLE 11 Middle East And Africa DST Market, by Region, 2017 – 2027 (US$ Mn)
TABLE 12 Alexion Pharmaceuticals, Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 13 Teva Pharmaceutical Industries Ltd.: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 14 Fresenius Kabi AG: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 15 Pharmacia & Upjohn (a subsidary of Pfizer): Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 16 Lupin Ltd.: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 17 Sagent Pharmaceuticals, Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 18 Zydus Pharmaceuticals, Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 19 Sandoz Inc. (a subsidiary of Novartis): Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 20 Alkem Laboratories Ltd.: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 21 Mylan Pharmaceuticals, Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 22 Chugai Pharmaceutical Co., Ltd.: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 23 MedImmune LLC: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 24 RemeGen, Ltd.: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
FIG. 1 Devic’s Syndrome Treatment (DST): Market Segmentation
FIG. 2 Global DST Market Share, by Type of Drugs, 2018 (US$ Mn)
FIG. 3 Global DST Market, by Geography, 2018 Vs 2027 (Value %)
FIG. 4 Attractive Investment Proposition, by Geography, 2018
FIG. 5 Market Competition Landscape, by Key Players, 2018
FIG. 6 Global Eculizumab Market for DST, 2017 – 2027 (US$ Mn)
FIG. 7 Global Methylprednisolone Market for DST, 2017 – 2027 (US$ Mn)
FIG. 8 Global Azathioprine Market for DST, 2017 – 2027 (US$ Mn)
FIG. 9 Global Mycophenolate Mofetil Market for DST, 2017 – 2027 (US$ Mn)
FIG. 10 Global Rituximab Market for DST, 2017 – 2027 (US$ Mn)
FIG. 11 Global Satralizumab Market for DST, Till 2027 (US$ Mn)
FIG. 12 Global MEDI-551 Market for DST, Till 2027 (US$ Mn)
FIG. 13 Global RC18 Market for DST, Till 2027 (US$ Mn)
FIG. 14 U.S. DST Market, 2017 – 2027 (US$ Mn)
FIG. 15 Canada DST Market, 2017 – 2027 (US$ Mn)
FIG. 16 U.K. DST Market, 2017 – 2027 (US$ Mn)
FIG. 17 Germany DST Market, 2017 – 2027 (US$ Mn)
FIG. 18 Rest Of Europe DST Market, 2017 – 2027 (US$ Mn)
FIG. 19 Japan DST Market, 2017 – 2027 (US$ Mn)
FIG. 20 China DST Market, 2017 – 2027 (US$ Mn)
FIG. 21 Rest Of Asia Pacific DST Market, 2017 – 2027 (US$ Mn)
FIG. 22 Brazil DST Market, 2017 – 2027 (US$ Mn)
FIG. 23 Mexico DST Market, 2017 – 2027 (US$ Mn)
FIG. 24 Rest Of Latin America DST Market, 2017 – 2027 (US$ Mn)
FIG. 25 GCC DST Market, 2017 – 2027 (US$ Mn)
FIG. 26 Rest Of Middle East And Africa DST Market, 2017 – 2027 (US$ Mn)